Production Pilot / Commercial

 

Sino Chemsource Ltd, specializes in the scaling up of laboratory processes and satisfying the increasing regulatory demands for the supply of bulk chemicals.

We are able to design a personalized process for your product utilising our dedicated and talented R&D teams.

We are targeted on transforming the initial synthesis into a robust commercial process, allowing the large scale manufacture of an organic intermediate or drug substance in a safe, efficient, cost-effective, and environmentally responsible manner meeting all the customer needs. 

 

Our Production Strengths:

 

(i) Robust scale up routes established for catalogue / laboratory compounds.

(ii) Developmental risk analysis is conducted on each process step before large-scale manufacturing is undertaken, to minimise HSE risks.

(iii) Innovative routes can be applied to the most challenging of out-sourced projects using advanced chemical technologies, including flow chemistry & bio-catalysis.

(iv) Analytical chemical development to control, quality, purity, and impurities.

 

We can often deliver on what seems impossible from the initial technology package provided by our customers.

 

CAPACITY AND REACTION TYPES

 

We have over 500,000 L of vessel capacity available on several sites for our projects, with vessels ranging from 50L -5,000 L and operating temperature ranges from -780C to 2400C

We are specialist at producing non-GMP intermediates for API manufacturing, and among others often undertake the following reactions at our sites:

 

C-C Bond Formation:

 

Friedel-Crafts (alkylation and acylation) reactions

Grignard reaction

Lithiation

Suzuki Coupling

Witting Reaction

 

Functional Group Transformation:

 

Amination

Bromination

Chlorination

Diazotization

Fluorination

Hydrogenation

Oxidation

Reduction